Tagged: Phenyl alanine

trial 4 0

Answer- Case study- Epilepsy

Question of the day A 12-year-old boy develops convulsions. After running an electroencephalogram (EEG), a neurologist determines that the child has epilepsy. He is started on Benzodiazepine, which promotes the activity of GABA. GABA is derived from the amino acid glutamate via which of the following biochemical reactions? A. Deamination B. Decarboxylation C. Hydroxylation D. Iodination E. Methylation Answer- The correct answer is B- Decarboxylation, Glutamic acid undergoes decarboxylation to yield GABA. The reaction is catalyzed by Glutamic acid decarboxylase that requires vitamin B6-P as a coenzyme. GABA is an inhibitory neurotransmitter and is thus helpful in controlling convulsions. Deamination...

trial 4 0

Answer- Case study- Oral contraceptives induced vitamin deficiencies

Case Details Oral contraceptives are known to lower blood levels of folate and vitamin B6. Which of the following conversion processes might be directly affected? A. Ornithine to Citrulline B. Histidine to histamine C. Glutamate to Glutamine D. Propionyl co A to Methyl malonyl co A E. Phenyl alanine to Tyrosine Answer- B- The correct answer is conversion of Histidine to histamine. The reaction is catalyzed by decarboxylase that requires B6-P as a cofactor (Figure-1) that gets deficient in women upon long-term oral contraceptive usage. Folic acid is not required in this reaction. Figure-1- Decarboxylation of Histidine is carried out...

trial 4 0

Answer- Case study- Amino acid supplements- A 27- year-old, semiprofessional tennis player seeks advice from a hospital-based nutritionist…

AMINO ACID METABOLISM A 27- year-old, semiprofessional tennis player seeks advice from a hospital-based nutritionist concerning his diet supplements. His coach had given him amino acid supplements consisting of phenyl alanine and tyrosine. The rationale was that these precursors to several neurotransmitters will “help his brain focus” on his game. In reality, the excess amino acids are used for energy, with a poor and eclectic diet. Phenyl alanine upon metabolism enters TCA cycle as which of the following? A. Oxaloacetate B. Fumarate C. Succinyl co A D. Citrate E. α- Keto glutarate Answer- The right answer is B- Fumarate. Phenyl...

trial 4 1

Case study- Amino acid supplements-A 27- year-old, semiprofessional tennis player seeks advice from a hospital-based nutritionist concerning his diet…

QUESTION OF THE DAY AMINO ACID METABOLISM A 27- year-old, semiprofessional tennis player seeks advice from a hospital-based nutritionist concerning his diet supplements. His coach had given him amino acid supplements consisting of phenyl alanine and tyrosine. The rationale was that these precursors to several neurotransmitters will “help his brain focus” on his game. Figure- Amino acid supplements In reality, the excess amino acids are used for energy, with a poor and eclectic diet. Phenyl alanine upon metabolism enters TCA cycle as which of the following? A. Oxaloacetate B. Fumarate C. Succinyl co A D. Citrate E. α- Keto glutarate...

trial 4 0

Answer- Case study- Hartnup disease- A 28- year-old man complains of a rash on his sun- exposed skin, diarrhea and loss of balance..

A 28- year-old man complains of a rash on his sun- exposed skin, diarrhea and loss of balance. His urinalysis results are significant for an increase in neutral amino acids. The patient is diagnosed with Hartnup’s disease that occurs due to a defective transport of neutral amino acids in the kidney. Apart from tryptophan which of the following amino acids would have been found in urine? A. Lysine B. Arginine C. Histidine D. Phenyl alanine E. Glutamic acid Answer The right option is D- Phenyl alanine. Hartnup disease is an autosomal recessive disorder caused by impaired neutral (i.e., mono amino...

trial 4 0

Case study- Hartnup’s disease- A 28- year-old man complains of a rash on his sun exposed skin, diarrhea and ..

22/01/2014 Amino acid chemistry QUESTION OF THE DAY A 28- year-old man complains of a rash on his sun exposed skin, diarrhea and loss of balance. His urinalysis results are significant for an increase in neutral amino acids. The patient is diagnosed with Hartnup’s disease that occurs due to  defective transport of neutral amino acids in the kidney. Apart from tryptophan which of the following amino acids would have been found in urine? A. Lysine B. Arginine C. Histidine D. Phenyl alanine E. Glutamic acid Figure- Patient with hartnup disease showing pellagra like rashes For answer- Follow the link http://usmle.biochemistryformedics.com/answer-case-study-hartnup-disease-a-28-year-old-man-complains-of-a-rash-on-his-sun-exposed-skin-diarrhea-and-loss-of-balance/...

Copy Protected by Chetan's WP-Copyprotect.