Tagged: Ornithine

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Amino acids in the post absorptive state ?

Question of the day During a medical rotation, a medical student volunteered for a respiratory physiology exam that determines basal metabolic rate and the respiratory quotient. She followed the protocol for a resting individual in the post absorptive state. Which of the following amino acids would be found in the highest concentration in serum? A. Alanine and Glutamine B. Arginine and Ornithine C. Glutamate and Aspartate D. Branched chain amino acids E. Hydrophobic amino acids   Figure- Post absorptive state For answer follow the link http://usmle.biochemistryformedics.com/answer-to-the-question-amino-acids-in-the-post-absorptive-state/ Please help Biochemistry for Medics by “CLICKING ON THE ADVERTISEMENTS” every time you visit...

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Case study- Hyperammonemia and Orotic aciduria

Question of the day A newborn becomes lethargic and drowsy 24 hour after birth. Blood analysis shows hyperammonemia, coupled with Orotic aciduria. This individual has an enzyme deficiency that leads to an inability to directly produce which of the following? A. Carbamoyl phosphate B. Ornithine C. Citrulline D. Argininosuccinate E. Arginine   Figure- Structure of Orotic acid For answer follow the link http://usmle.biochemistryformedics.com/answer-case-study-hyperammonemia-and-orotic-aciduria/ Please help Biochemistry for Medics by “CLICKING ON THE ADVERTISEMENTS” every time you visit us. Thank you!

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Answer- Case study- Oral contraceptives induced vitamin deficiencies

Case Details Oral contraceptives are known to lower blood levels of folate and vitamin B6. Which of the following conversion processes might be directly affected? A. Ornithine to Citrulline B. Histidine to histamine C. Glutamate to Glutamine D. Propionyl co A to Methyl malonyl co A E. Phenyl alanine to Tyrosine Answer- B- The correct answer is conversion of Histidine to histamine. The reaction is catalyzed by decarboxylase that requires B6-P as a cofactor (Figure-1) that gets deficient in women upon long-term oral contraceptive usage. Folic acid is not required in this reaction. Figure-1- Decarboxylation of Histidine is carried out...

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Case- Oral contraceptive induced Vitamin deficiencies

Question of the day Oral contraceptives are known to lower blood levels of folate and vitamin B6. Figure- Oral contraceptives Which of the following conversion processes might be directly affected ? A. Ornithine to Citrulline B. Histidine to histamine C. Glutamate to Glutamine D. Propionyl co A to Methyl malonyl co A E. Phenyl alanine to Tyrosine For answer follow the link http://usmle.biochemistryformedics.com/answer-case-study-oral-contraceptives-induced-vitamin-deficiencies/ Please help Biochemistry for Medics by “CLICKING ON THE ADVERTISEMENTS” every time you visit us. Thank you!

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