Tagged: leucine

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An amino acid that acts as a component of histones and a precursor for Nitric oxide (NO)

The general structure of chromatin has been found to be remarkably similar in the cells of all eukaryotes. The most abundant proteins associated with eukaryotic DNA (somewhat more than half its mass) are histones, a family of basic proteins rich in the positively charged amino acids that interact with the negatively charged phosphate groups in DNA. Which of the following amino acids acts as a component of histones and a precursor for Nitric oxide (NO)? A. Arginine B. Histidine C. Lysine D. Asparagine E. Leucine The correct answer is- A- Arginine. Histones are nucleoproteins, rich in basic amino acids such...

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A common intermediate of Urea and TCA cycle

Question of the day Which one of the following can be converted to an intermediate of either the citric acid cycle or urea cycle? A. Tyrosine B. Lysine C. Leucine D. Tryptophan E. Aspartate Answer- The correct answer is- E -Aspartate. 1) Role of Aspartate in urea cycle Aspartate participates in urea cycle for condensation with citrulline to form Argino succinic acid. The reaction is catalyzed by Argino succinic acid synthetase (Aspartate provides one out of the two nitrogens of urea, the other nitrogen is contributed by Glutamate). In the subsequent reaction, Argino succinic acid undergoes a lytic reaction to...

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Which amino acid is both glucogenic as well as ketogenic ?

A 54-year-old male who was diagnosed with HIV (human immuno deficiency virus) infection 2 years back, is currently in the terminal stage. He is now cachectic and having a difficult time obtaining any caloric intake yet he refuses to take a naso gastric or gastric feeding tube. Since his muscle and organs are metabolically active, which of the following amino acids will produce both glucose and ketone bodies as an energy source? A. Alanine B. Tyrosine C. Proline D. Glycine E. Leucine The correct answer is B- Tyrosine. Amino acids can be classified based on their metabolic fate- I) Purely...

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Case study- Starvation

Case details A 25 –year-old woman living alone became severely depressed after the termination of her engagement. Two months later, she was brought to the emergency room by a friend because of weakness and lethargy. She appeared thin and pale. Questioning revealed that she had not eaten for several weeks. Analysis of a plasma sample indicated elevated levels of acetoacetate, β hydroxybutyrate, and blood urea nitrogen (BUN). However her plasma glucose concentration was within normal limits. She was hospitalized, given intravenous feeding and antidepressant medications and subsequently shifted to an 1800 Cal (7500 kJ) diet. Her recovery was uneventful. During...

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