Tagged: Hexokinase

trial 4 0

Fructose 2, 6 Bis phosphate and regulation of glycolysis

Case details A patient presents with dizziness, fatigue and tremors. A finger stick test indicates blood glucose of 36mmol/L. Of the allosteric activators of glycolysis in the liver, which of the following is the most important in maintaining a normal blood glucose level? A. Citrate B. ATP C. Fructose 2, 6 bisphosphate D. Glucose-6-Phosphate E. Acetyl Co A The correct answer is- C- Fructose 2,6 bisphosphate Generally, enzymes that catalyze essentially irreversible steps in metabolic pathways are potential sites for regulatory control.  Although most of the reactions of glycolysis are reversible, three are markedly exergonic and must therefore be considered...

trial 4 1

Case study- Enzymology- A teenager finishes eating a hot fudge sundae and a milk shake…

ENZYMOLOGY A teenager finishes eating a hot fudge sundae and a milk shake. As her blood sugar rises, the liver recruits both Glucokinase (km = 10.0m M) and Hexokinase (km = 0.10mM) to metabolize the glucose. Which of the following is a correct statement about the kinetics of these two enzymes? A. Hexokinase will metabolize 100 times more glucose molecules B. Hexokinase will lower the energy of activation more than glucokinase C. Hexokinase has a much higher affinity to glucose than glucokinase D. Hexokinase will have a higher Vmax than glucokinase E. Hexokinase will be induced more than glucokinase by...

trial 4 0

‘Hereditary fructose Intolerance’- Case discussion

QUESTION OF THE DAY A 3-month-old girl is brought to the pediatrician due to fussiness and lethargy. According to the parents, the baby was just fine until the mother needed to return to work, and the baby was being switched from breast milk to baby foods, formula, and fruit juices. At that time, the child cried while feeding, sometimes vomited, and had been lethargic. The baby’s appetite seemed to have worsened. The parents thought that if only formula was used, the baby was better, but they really could not remember. Which possible enzyme defect might lead to this case presentation?...

trial 4 1

Case study- Metabolic disorder- A 3-month-old girl is brought to the pediatrician due to fussiness and lethargy….

QUESTION OF THE DAY A 3-month-old girl is brought to the pediatrician due to fussiness and lethargy. According to the parents, the baby was just fine until the mother needed to return to work, and the baby was being switched from breast milk to baby foods, formula, and fruit juices. At that time, the child cried while feeding, sometimes vomited, and had been lethargic. The baby’s appetite seemed to have worsened. The parents thought that if only formula was used, the baby was better, but they really could not remember. Which possible enzyme defect might lead to this case presentation?...

Copy Protected by Chetan's WP-Copyprotect.