Tagged: Glucose transporters

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Glucose transporter-1(GLUT-1)

Glucose travels across the cell membrane on a transport protein. Hereditary deficiency of GLUT-1, insulin -independent transporter, results in decreased glucose transport. Patients manifest with intractable seizures in infancy and a developmental delay. GLUT-1 transporter is expressed in which of the following cell types? A. Liver, kidney and pancreatic β cells B. Brain (neurons) C. Adipose tissue, skeletal muscle and cardiac muscle D. Erythrocytes, Blood -brain barrier, blood-retinal barrier E. Intestinal epithelium, Spermatozoa. The correct answer is- D, Erythrocytes, Blood -brain barrier, blood-retinal barrier. Basic concept Glucose transport across the cell membrane is a facilitated transport, a carrier mediated transport....

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