Category: Molecular genetics

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Type 1 Diabetes mellitus – Etiology ?

A 10- year-old child has been diagnosed with Juvenile diabetes mellitus (type 1 diabetes mellitus). This is a disorder of carbohydrate metabolism caused by insulin deficiency. The disease is often preceded by viral infection with inflammation of the beta cells of pancreas, but also exhibits genetic predisposition with a 40-50% concordance rate in monozygotic twins and clustering in families. Type 1 diabetes mellitus may be best described as a A. Sex linked disorder B. Congenital disorder C. Sporadic disorder D. Multifactorial disorder E. Mendelian disorder Answer- The correct answer is- D, Multifactorial disorder. Many common diseases are caused by a combination...

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