Case study- HIV infection – A 33 -year-old, homosexual man is recently diagnosed..

Question of the day

A 33 -year-old, homosexual man is recently diagnosed with human immuno deficiency virus (HIV) infection. His CD4+T- cell count is dramatically decreased, and he has a high HIV viral load.

HIV structure

 

Figure- A cross sectional view of HIV structure

He is referred to an infectious disease clinic where they begin him on a nucleoside analog. These drugs inhibit DNA synthesis because they lack which of the following properties required for the normal DNA polymerization?

A. 5′- phosphate

B. 3′ – hydroxyl

C. 7- methyl Guanosine triphosphate

D. Poly (A) tail

E. A consensus sequence

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