Question of the day
A 33 -year-old, homosexual man is recently diagnosed with human immuno deficiency virus (HIV) infection. His CD4+T- cell count is dramatically decreased, and he has a high HIV viral load.
Figure- A cross sectional view of HIV structure
He is referred to an infectious disease clinic where they begin him on a nucleoside analog. These drugs inhibit DNA synthesis because they lack which of the following properties required for the normal DNA polymerization?
A. 5′- phosphate
B. 3′ – hydroxyl
C. 7- methyl Guanosine triphosphate
D. Poly (A) tail
E. A consensus sequence
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